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In preclinical models, BPC-157 is primarily associated with angiogenic and nitric oxide signaling pathways

In studies using human gingival and periodontal stem cells [4, 45], Epitalon enhanced the expression of: Nestin (neural progenitor marker) GAP43 (axon growth) -Tubulin III and Doublecortin (neuronal differentiation and migration) Together, these shifts suggest Epitalon may prime stem cells toward neuronal lineage, hinting at applications in regenerative neurology or brain injury recovery models

Water retention or mild bloating: Small amounts of fluid retention can occur when starting peptide analogues of growth hormone because growth hormone causes sodium and water retention in the tissues, resulting in slight puffiness or bloating

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